1. Personality
Some people may be more at risk of depression because of their personality, particularly if they have a tendency to worry a lot, have low self-esteem, are perfectionists, are sensitive to personal criticism, or are self-critical and negative.
2. Serious medical illness
The stress and worry of coping with a serious illness can lead to depression, especially if you’re dealing with long-term management and/or chronic pain.
3. Genetic
Depression may be an inherited condition. You may have a higher likelihood of experiencing a depressive disorder at some point in your life if you have a family member with depression. The exact gene involved in this is unknown.
4. Biological causes of depression
Certain illnesses or medical conditions can also cause depression. These are – hormonal disorders (for example perimenopause or hypothyroidism in women), cancer, heart disease leading to a stroke, diabetes, Parkinson’s disease and Alzheimer’s disease. A long-term illness that goes on for years is also a cause of depression. Advanced age combined with various illnesses can lead to manic depression. Some people may suffer from multiple illnesses at the same time. This can tire the body physically, and the mind emotionally, resulting in depression.
5. Dietary
Many people across the world do not have access to a proper diet and their daily intake of nutrients, proteins, vitamins and minerals remain deficient. They are at a high-risk category. Deficiency of Folic Acid and Vitamin B12 is related to the occurrence of depression. On the contrary, people who regularly consume rich food which makes them obese, also suffer from depression.
6. Environmental
The onset of certain seasons also result in depression. These are commonly referred to as Seasonal Affective Disorder. The exact cause is reduced or increased amount of sunlight which disturbs the chemical balance of the body and especially the chemistry of the brain. This in turn causes either excess or inhibited production of mood controlling chemicals that can result in depression.
7. Hormonal
Changes in hormone production or functioning could also lead to the onset of depressive states. Any changes in hormone states — including menopause, childbirth, thyroid problems, or other disorders — could cause depression.
Sources:
https://www.beyondblue.org.au/the-facts/depression/what-causes-depression
http://www.healthline.com/health/depression/causes#Causes3
http://www.rxadvices.com/depression-symptoms/5-important-causes-of-depression/
http://www.immunadue.co.za